EC Gastroenterology and Digestive System

Introduction: The incidence of CP in developed countries ranges from 5 - 10 cases per 100,000 population; in the world as a whole - 1.6-23 cases per 100,000 population per year (19-22). There is a tendency in the world to increase the incidence of acute and chronic pancreatitis, over the past 30 years - by more than 2 times.

Aim of the Study: The aim is to identify the possibility of changing the motor function of the gastrointestinal tract and lesions of the oral cavity in chronic pancreatitis.

Materials and Methods: The motor function of the gastrointestinal tract was recorded electromyographically. The electromyogram curve was used to evaluate the amplitude-frequency characteristics of slow waves and spikes, the power of phase and tonic contractions, and propulsive activity. The study was conducted in a group of patients with chronic pancreatitis (48 patients), the comparison group consisted of 39 patients with gastritis C. Statistical analysis was carried out using the Statistika -16 software package at p < 0.05.

Results: In CP, pronounced hypermotor dyskinesia of all muscle groups of the stomach was observed with a predominance of spasm of the circular and partially oblique muscle layers, which determines a decrease in the propulsive activity of the stomach.

Moderate hypermotor dyskinesia of the small intestine in CP was revealed due to a marked decrease in the tone of the circular muscles, which may be due to secretory insufficiency in pancreatic pathology.

Hypermotor dyskinesia of the descending colon and colon as a whole was determined, which may be associated with the development of intestinal dysbiosis due to secretory insufficiency of the pancreas in CP.

Patients with pancreatic pathology often have various immune disorders. The close connection of the pancreas and salivary glands is demonstrated by the presence of antibodies to the tissue antigen of the salivary glands in 1/3 of patients with chronic pancreatitis with the presence of antibodies to the tissue antigen of the pancreas.

Conclusion: Electromyography can be used to study the motor function of the gastrointestinal tract in chronic pancreatitis.

The pathology of the pancreas in CP determines the nature of the violation of the motor function of the gastrointestinal tract - hypomotor dyskinesia of the stomach and hypermotor dyskinesia of the small and large intestine due to secretory insufficiency of the pancreas and developing intestinal dysbiosis.

 Keywords: Motor Activity of the Gastrointestinal Tract; Secretory Insufficiency of the Pancreas; Intestinal Dysbiosis

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